Atromed 100 ml ( Atropine )
Each 1 ml contains:
Atropine Sulphate 600 µg
Equivalent to Atropine base 249.84 µg
Atropine, the prototypical muscarinic blocking agent, is an alkaloid extract from the belladonna plants.
Atropine sulphate interacts with muscarinic receptors of effector cells and by occupying these sites prevents Ach from affixing to the receptors area. Physiologic responses to parasympathetic nerve impulses are thereby attenuated.
Preanesthetic with volatile anesthesia in pet animal.
Antimuscarinic use (Drying secretions - Gastro-intestinal disorders characterized by smooth muscle spasm).
Antidote for Organophosphorus poisoning.
Target Species: Horses, cattle, sheep, pigs, dogs & cats
I) Antimuscarinic use, by subcutaneous injection.
Horses, cattle: 5 – 10 ml of Atromed / 100 kg body weight.
Sheep: 6.67 – 13.33 ml of Atromed / 50 kg body weight.
Pigs: 1.67 – 3.33 ml of Atromed / 50 kg body weight
Dogs, cats: 0.5 – 0.8 ml of Atromed / 10 kg body weight
II) Organophosphorus poisoning.
By subcutaneous injection, 4.2 – 33.3 ml of Atromed / 100 kg body weight at approximately 3–4 hour intervals until clinical signs of poisoning relieved.
In severe cases, a quarter of the dose may be given by intramuscular or slow intravenous injection and the remainder by subcutaneous injection.
Warnings & Precautions
Systemic atropine should be used cautiously in horses as it may decrease gut motility and induce colic in susceptible animals.
It may also reduce the arrhythmogenic doses of epinephrine.
Use of atropine in cattle may result in inappetance and rumen stasis which may persist for several days.
Cattle: slaughter 14 days (antimuscarinic use), 28 days (antidote use).
Milk:3 days (antimuscarinic use), 6 days (antidote use).
Sheep, pigs:slaughter 14 days (antimuscarinic use), 28 days (antidote use)
Store at temperature not exceeding 30°c & used within 50 days after opening when stored at temperature not exceeding 30°c.